Matthew Perry had dozens of life-saving surgeries, 15 trips to rehab clinics and  spent $9 million trying to get clean as he struggled with drugs and alcohol.

Perry died aged 54 'after drowning in his jacuzzi at home,' sources said on Saturday although no drugs were found on scene and there was no indication of foul play.

First responders were called to reports of a 'cardiac arrest' at his Los Angeles abode, according to law enforcement sources.

Perry previously detailed his battle with drug and alcohol addiction in tell-all autobiography Friends, Lovers, And The Big Terrible Thing, released in November last year.

In 2019, he narrowly escaped death after his colon burst due to opioid overuse.

He described the moment his loved ones raced to the Los Angeles hospital where they were told the then 49-year-old had only a two per cent chance of surviving the night.

He slipped into a coma for two weeks and when he came discovered he had been fitted with the colostomy bag he had to wear for the next nine months.

Just two years later he suffered another brush with death at a rehab facility in Switzerland. 

Doctors administered a sedative which interacted with the opioids in his ravaged body causing his heart to stop beating.

They managed to resuscitate him but broke eight ribs in the process, forcing him to pull out of a role alongside Meryl Streep in the film Don't Look Up, a lost opportunity he described as 'heartbreaking'.

The two near-death experiences were a world away from his role as wise-cracking, hopelessly romantic Chandler Bing in Friends.

The role eventually earned him around $1 million per episode, making him one of the best-paid actors in the world.

But for Perry, fame came at an extremely high price, not least the $9 million he reckons he has spent on trying to remain sober.

Estimating that he made some 6,000 visits to Alcoholics Anonymous, he was also in rehab 15 times and underwent 12 surgeries to save his life.

At one point, his gums were so diseased from his debauched lifestyle that his top front teeth fell out as he bit into toast spread with peanut butter, and he found himself carrying them to the dentist in a plastic bag.

He insisted he never turned up to the Friends set while high or drunk, but admitted his physical on-screen appearance indicated what substance he was using at the time.

While making the show, which ran between 1994 and 2004, Perry's weight varied from 9st 2lb to 16st 1lb. If he was skinny, it was painkillers. 

If he was carrying weight, it was drink, and there were many times when he turned up for filming hungover.

On one occasion during filing in the  iconic Central Perk coffee shop, he passed out on the famous orange couch and co-star Matt LeBlanc, who played Joey, had to nudge him awake to say his line.

On another occasion, Jennifer Aniston came to his trailer and called him out for his drinking, telling him 'in a weird but loving way' that 'we can smell it'.

In 1996 he began dating Julia Roberts following her brief appearance in the sitcom — by then a global ratings hit — as Susie Moss, Chandler's girlfriend. 

Roberts agreed to Perry's request for a cameo only if he'd write her a paper on quantum physics, which he duly faxed to her the next day.

Their off-screen romance was brief, though, lasting only two months before Perry ended it.

'I had been constantly certain that she was going to break up with me... so instead of facing the inevitable agony of losing her, I broke up with the beautiful and brilliant Julia Roberts,' he said.

'She might have considered herself slumming it with a TV guy, and TV guy was now breaking up with her. I can't begin to describe the look of confusion on her face.'

Behind this decision, and indeed many of his problems with addiction, laid Perry's conviction that he is 'broken, bent, unlovable'.

He traced these feelings in part to his childhood and the departure of his father Josh Perry whilst he was still a baby.

'If I drop my game, my Chandler, and show you who I really am, you might notice me, but worse, you might notice me and leave me,' he wrote.

His drinking began with beer and cheap wine when he was only 14 years old, and by his 21st birthday party it was already showing signs of being out of control. 

He moved to Los Angeles to pursue his childhood dream of stardom, he appeared in several television shows before successfully auditioning for Friends.

The six-strong regular cast hit it off from the start, and their enduring friendship off camera was undoubtedly a big feature in the chemistry on set, but Perry still found filming hugely stressful.

'I felt like I was gonna die if the live audience didn't laugh,' he admitted on the reunion show in 2021. 

'And I would sweat and just, like, go into convulsions. I felt like that every night.'

The enormous success of the show and the subsequent paparazzi attention for the six previously relatively unknown actors meant 'every single moment of our lives being documented in public for all to see for ever'.

This did not help with Perry's increasingly heavy drinking, and he also developed an addiction to Vicodin, a painkiller he took following a jet-ski accident soon after he joined the show. 

The maximum daily dosage is eight tablets but, by the end of the third season of Friends, he was swallowing around 55 a day.

The search for more pills became a 'full-time job: making calls, seeing doctors, faking migraines, finding crooked nurses who would give me what I needed.

'It's exhausting but you have to do it or you get very sick,' he told the New York Times at the time.

'I wasn't doing it to feel high or to feel good. I certainly wasn't a partyer. I just wanted to sit on my couch, take five Vicodin and watch a movie. That was heaven for me. It no longer is.'

Perry also revealed he would go to the 'open houses' held by American estate agents to showcase a property, just so he could steal pills from the medicine cabinets.

In 1995, a former girlfriend with whom he was still friendly insisted he see a doctor about his addictions.

This led to the first of many stints in rehab. But even as he left, he knew he was going to drink again — lasting only nine weeks before once again hitting the bottle.

'Addiction wakes up before you do,' he said, 'and it wants you alone. As soon as you raise your hand and say: 'I'm having a problem,' alcohol sneers: 'You're gonna say something about it? Fine, I'll go away for a while. But I'll be back.' It never goes away for good.'

Perry attributed his survival, in part, to the support he got from his inseparable Friends co-stars, describing how they ate every meal together and played poker in between scenes. 

'They were understanding and they were patient,' he said in an interview with People magazine last week.

'It's like penguins. When one is sick, the other penguins surround it and prop it up until that penguin can walk on its own. That's kind of what the cast did for me.'

Between takes, he'd get on the exercise bike installed backstage at the request of cardio-enthusiasts Jennifer Aniston and Courteney Cox, and cycle furiously in a bid to get his hungover brain firing on all cylinders. But there was no escaping his addictions.

'I didn't know how to stop,' he told People at the time.

'If the police came over to my house and said: 'If you drink tonight, we're going to take you to jail,' I'd start packing. I couldn't stop because the disease and the addiction is progressive. So it gets worse and worse as you grow older.'

By the summer of 1996, when Perry began filming Almost Heroes, a comedy directed by Christopher Guest, he was hardly ever eating — a full stomach seemed to get in the way of the 'high'.

He said he was also throwing up regularly, keeping two towels next to the lavatory, one for wiping up the vomit, the other 'to wipe away the tears'.

Perry explained that he has always drawn the line at taking heroin, especially after his cherished co-star Chris Farley — a comedian best known for U.S. TV sketch show Saturday Night Live who was known to use the drug — died of an overdose aged 33 in 1997.

It was a choice Perry credited with saving his life. But his problems got so bad that he eventually had to have a 'sober companion' — a person who helps addicts in their recovery — accompany him to the Friends set.

'Everyone would ask me if I was all right, but no one wanted to stop the Friends train because it was such a money-maker,' he wrote

'My greatest joy was also my biggest nightmare. I was this close to messing up a wonderful thing.'

He was at a particularly low ebb when he filmed one of Friends' most-anticipated scenes — Chandler's wedding to Monica, which aired in 2001.

Describing it as 'the iconic moment on the iconic show', he revealed that after shooting had finished for the day, he was collected by a sober companion in a pick-up truck and driven back to the rehab center where he was then staying.

Two years later, he co-starred in the rom-com Serving Sara with Elizabeth Hurley, while using methadone (the heroin substitute also used to wean people off Vicodin), along with the anxiety medication Xanax and cocaine, all washed down with around a pint-and-a-half of vodka a day.

He turned up to film one scene, only to realize it had already been shot a few days earlier. 

The production closed down while he went to rehab, and a breach of contract saw him billed for around half a million pounds by the producers. The film was a flop.

Although he's had various movie and TV roles since the final season of Friends aired in May 2004, his role as Chandler Bing is the one with which he will always be identified — perhaps because they had so much in common.

'I was Chandler,' he wrote, explaining that both he and his most famous character use humor to compensate for their insecurities, and they also share relationship anxieties and self-sabotaging behavior.

The difference, as the LA Times has pointed out, is that Chandler finds happiness, marrying Monica and adopting their twins.

Perry, by contrast, described how deeply he regretted how his drug and alcohol abuse have cost him relationships.

Following short-lived romances with actresses including Scream star Neve Campbell, The Hangover's Heather Graham and Yasmine Bleeth, who starred in Baywatch, it seemed as though he had finally found happiness when, in November 2020, he proposed to literary agent Molly Hurwitz, 29, his girlfriend of two years.

However, the relationship ended seven months later, with a close friend of Hurwitz's telling the American celebrity gossip magazine In Touch: 'You can only help someone so much. He is in a really dark place and pals fear he may have relapsed.'